Diphenhydramine (Benadryl) Dosage Table  
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Diphenhydramine (Benadryl, etc.) Dosage Table
Child's weight (pounds)20-2425-3738-4950-99100+lbs.
Liquid 12.5 mg/ 1 teaspoon (tsp)¾12--tsp
Liquid 12.5 mg/5 milliliters (ml)457.510--ml
Chewable 12.5 mg--124tablets
Tablets 25 mg--½½12tablets
Capsules 25 mg------12caps

Indications: Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:

  • AGE LIMITS: For allergies, don't use under 1 year of age (Reason: it's a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).
  • DOSAGE: Determine by finding child's weight in the top row of the dosage table
  • MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication.  If not, medicine syringes are available at pharmacies. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.  
  • ADULT DOSAGE: 50 mg
  • FREQUENCY: Repeat every 6 hours as needed
  • CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets.

Author and Senior Reviewer: Barton D. Schmitt, M.D.

Content Set: Pediatric HouseCalls Symptom Checker

Pediatric HouseCalls Symptom Checker